Tijelo ima vlastiti endokanabinoidni sustav koji regulira mnoge funkcije u organizmu, no kada on zakaže, u pomoć priskače kanabis, čiji se kanabinoidi savršeno uklapaju s tjelesnim kanabinoidnim receptorima. Studije dokazuju da ovakva aktivacija može potaknuti formiranje kostiju i smanjiti njihovu razgradnju.
Studija iz 2009. godine navodi: “Aktivna komponenta kanabisa, Delta (9) tetrahidrokanabinol, aktivira i CB1 i CB2 kanabinoidne receptore, čime se imitira djelovanje endogenih kanabinoida. CB1 je pretežno neuronski i posreduje u psihotropnim učincima. CB2 je pretežno izražen u perifernim tkivima, uglavnom u patološkim stanjima. Do sada su glavni endokanabinoidi, anandamid i 2-arahidonoilglicerol, pronađeni u kostima na “moždanim” razinama. CB1 receptor je prisutan uglavnom u skeletnim simpatičkim živcima, čime igra ulogu u reguliranju formiranja kostiju. CB2 je izražen u osteoklastima i osteoblastima, stimulira formiranje kostiju i sprječava njihovu razgradnju.”
Ista studija navodi i veliku ulogu kanabinoida u sprječavanju osteoporoze, a istraživanja su provedena i na CB2 mutiranim miševima, kao i ljudima. Uočeno je da je glavna uloga CB2 povezana uz održavanje remodeliranja kostiju u ravnoteži, čime štiti kostur od gubitka koštane mase povezane sa starenjem. Kod ljudi, polimorfizmi CNR2, gena koji kodira CB2, su čvrsto povezani s osteoporozom. Predkliničke studije su pokazale da sintetski CB2 spašava gubitak kostiju uzrokovan ovariektomijom (uklanjanje janika). Zaključak studije je da ova izvješća otvaraju put novim istraživanjima za razvoj dijagnostičkih mjera za prepoznavanje osteoporoze i kanabinoida kao lijekova u borbi protiv osteoporoze.
Sve ovo potvrđuje i studija iz 2014., koja navodi: “Kanabinoidni receptor tip-2 (CB2) je izražen u osteoblastima i igra važnu ulogu u metabolizmu kostiju kroz regulaciju koštane mase i koštane razgradnje…”
Istraživanja koja dokazuju iznimnu ulogu kanabinoida u ljudskom organizmu ima mnogo, i ono što nama svima najviše treba jesu stručni ljudi koji će provoditi ovakva istraživanja, i koji će ih interpretirati na razumljiv način kako bi što više ljudi, običnih ljudi, a posebno onih iz oblasti politike, shvatilo nezamjenjivu ulogu kanabisa kao lijeka u slučajevima kada ljudski endokanabinoidni sustav zakaže.
Source: https://portalosuma.com
Piše: Irena Dujmušić
Os Uma
Even though I never thought of doing email marketing, this site completely changed the way I run my business now. Never seen emails going that cheap in my life: http://bit.ly/emails4less
Great post but I was wanting to know if you could write a litte more on this subject? I’d be very thankful if you could elaborate a little bit more. Many thanks!
I’ve been absent for some time, but now I remember why I used to love this blog. Thank you, I will try and check back more often. How frequently you update your web site?
Really this is an effective post from a consultant and thanks for sharing this high-quality information with us.
hi!,I like your writing so much! share we communicate more about your post on AOL? I require a specialist on this area to solve my problem. May be that’s you! Looking forward to see you.
Make money online by watching ads. High Payouts! https://adblast.alternet.com/r/viewmore
As a Newbie, I am always exploring online for articles that can be of assistance to me. Thank you
I’m not sure why but this web site is loading extremely slow for me. Is anyone else having this problem or is it a issue on my end? I’ll check back later and see if the problem still exists.
I like what you guys are up too. This sort of clever work and exposure! Keep up the amazing works guys I’ve incorporated you guys to blogroll.
I am a girl. one. no guys 😂
$5000 in real cash every single month?? Yes, it’s possible! Register to learn: http://bit.ly/2GypqBt
Would you say “No” to 37 tools that will build and automate your website, so you don’t have to touch it again? All for a price of peanuts – $15 – yeah, stupidly cheap for 37 automation tools that do all the hard work for you. One of the tools even creates banners for you lol! You will not find anything like this in your whole life! Go and grab your copy before all software is gone! Click here: Affiliate Bots 2.0
With havin so much content do you ever run into any issues of plagorism or copyright infringement? My site has a lot of exclusive content I’ve either written myself or outsourced but it appears a lot of it is popping it up all over the internet without my agreement. Do you know any methods to help protect against content from being ripped off? I’d genuinely appreciate it.
An interesting discussion may be worth comment. I think that you can write more on this topic, it might be considered a taboo subject but normally consumers are too little to chat on such topics. To another location. Cheers
Very good article. I am dealing with many of these issues
as well..
Thank you, I have just been looking for information about this subject for ages and yours is the best I’ve discovered till now. But, what about the conclusion? Are you sure about the source?
Oh, believe me! All of these studies and studies go out to my nose, but I’m trying to talk and transmit the truth and just the truth. Is it possible that everything is revealed and stories about cannabis are all false? But the possibility of fraud can not be ignored.
Aw, this was a very nice post. Finding the time and actual effort to create a great article…
but what can I say… I hesitate a whole lot and don’t
seem to get nearly anything done.
What can you lose If you do not like it, you may be right, and maybe you are not. Opportunity to reconsider and find your foundations. If you love it from the beginning without a critique, that’s not good at all. Change everything.
I found your site thanks a Google search. You have done a fine work. And it’s really nice to read you. I’ll definitely be back!
I discovered your site website on google and check a couple of your early posts. Preserve the really good operate. I merely extra encourage Feed to my MSN News Reader. Looking for forward to reading far more within you later on!…
I read this article completely regarding the difference of hottest and preceding
technologies, it’s awesome article.
💖
Thanks a lot for sharing this with all folks you
actually recognize what you’re talking approximately!
Bookmarked. Kindly additionally visit my website =). We will have a hyperlink trade agreement between us
Wow that was unusual. I just wrote an very long comment but after I
clicked submit my comment didn’t appear. Grrrr…
well I’m not writing all that over again. Regardless, just wanted to
say superb blog!
Many thanks for bothering to line all of this out for people. This particular posting was in fact very useful in my opinion.
In my opinion, greengold-zelenozlato.com does a great job of dealing with subjects like this! While ofttimes deliberately polemic, the material posted is more often than not well-written and challenging.
5/11/2019 In my opinion, greengold-zelenozlato.com does a excellent job of covering subject matter of this sort. While often deliberately contentious, the information is more often than not thoughtful and challenging.
Thankfulness to my father who told me concerning this webpage, this web site is actually amazing.
I like what you guys are up too. Such intelligent work and reporting! Carry on the excellent works guys I have incorporated you guys to my blogroll. I think it will improve the value of my web site
An intriguing discussion may be worth comment. I believe that you can write regarding this topic, it will not be a taboo subject but usually people are insufficient to talk on such topics. To the next. Cheers
Congrats for the noteworthy site you’ve created at greengold-zelenozlato.com. Your enthusiasm is definitely inspiring. Thanks again!
Cool blog! Is your theme custom made or did you download it
from somewhere? A design like yours with a few simple tweeks would really make my blog shine.
Please let me know where you got your theme. Kudos
I go to see day-to-day some blogs and sites to read articles or reviews, except this web site presents quality based writing.
Manchester United fc tröja
Hello! This is my 1st comment here so I just wanted to give a
quick shout out and say I really enjoy reading your posts.
Can you recommend any other blogs/websites/forums that deal with the same subjects?
Thank you! Athletic Bilbao Trikot Kinder
WOW just what I was searching for. Came here by searching for how to get help in windows 10
Can I simply just say what a comfort to find a person that truly knows what they’re
discussing on the net. You definitely understand how to bring
a problem to light and make it important. More people
need to read this and understand this side of your story.
It’s surprising you’re not more popular because you certainly have the gift.
I’m really enjoying the theme/design of your web site.
Do you ever run into any web browser compatibility issues?
A few of my blog readers have complained about
my site not working correctly in Explorer but looks great in Firefox.
Do you have any tips to help fix this problem?
It’s an remarkable post designed for all the web
people; they will take benefit from it I am sure.
I blog quite often and I genuinely thank you for your information.
Your article has truly peaked my interest. I am going to bookmark your
website and keep checking for new information about once
per week. I opted in for your RSS feed too.
Everything is very open with a very clear explanation of the issues.
It was truly informative. Your website is very useful.
Many thanks for sharing!
Spot on with this write-up, I truly believe that this site needs a lot more attention. I’ll probably be returning to read more, thanks for the advice!
Hello! This post could not be written any better! Reading
this post reminds me of my old room mate!
He always kept chatting about this. I will forward this post to him.
Fairly certain he will have a good read. Many thanks for sharing!
I used to be recommended this blog by way of my cousin. I am now not positive whether or not this submit is
written by him as nobody else recognize such exact about my
problem. You’re wonderful! Thank you!
This is the perfect blog for anybody who would like to find out about this topic.
You understand so much its almost tough to argue with you (not that
I actually would want to…HaHa). You definitely put a new spin on a topic that’s been written about for a long time.
Great stuff, just excellent!
A fascinating discussion is definitely worth
comment. I believe that you ought to write more about this issue, it may
not be a taboo matter but generally folks don’t speak about such subjects.
To the next! Kind regards!!