Trigeminalna neuralgija (TN) je jedan od najozbiljnijih bolnih poremećaja i obično se naziva i samoubilačka bolest. Trigeminalni živac je odgovoran za prijenos svih osjetilnih informacija s lica i glave. To uključuje, ali nije ograničeno na temperaturu, bol i osjećaj pritiska. Većina nas doživljava prednosti trigeminalnog živca, osjećamo vjetar na našim obrazima dok puše, ili možemo osjetiti klasičnu buku, a mi smo u stanju tolerirati bol i brzo je onesposobiti. Ako živčani snop postane nadražen ili oštećen, to može biti kvar na ekstremno bolne načine. Jedan blagi vjetar može se osjećati kao senzacija rezanja, probijanja, gorenja, boli u usta, zubima, očima, obrazu i uhu i može trajati nekoliko sati.
Vjeruje se da je najčešći uzrok trigeminalne neuralgije vaskularna kompresija živčanog paketa blizu onoga gdje se enervira s moždanim stabljikom. Tlak nadražuje živce, a živac više ne može ispravno funkcionirati. Na kraju iritacija dovodi do demijelinacije i teške neuralne disfunkcije. Disfunkcionalni živac postaje preosjetljiv i ne može dugo prekinuti osjećaj nakon uklanjanja odgovarajućeg poticaja. Kao rezultat toga, netko tko pati od tog stanja doživjet će paroksizmalnu alodiniju, iznenadni napad ekstremne boli koji je pokrenut ne-bolnim podražajima kao što je pero na obrazu. Ostali sumnjivi uzroci uključuju pritisak od tumora, ugriz cističnog pauka na pravome mjestu, oštećenja od multiple skleroze, prometne nesreće, operacije lica ili čak piercing tijela.
Prva terapija koja se tipično koristi za bolesnike koji pate od TN su lijekovi. Nažalost, lijekovi ne djeluju uvijek i ljudi koji koriste lijekove vjerojatno će patiti od neželjenih nuspojava. Nakon što se lijekovi dokažu da nisu korisni, mnogi će se ljudi obratiti kirurškom zahvatu koji nosi čitav drugi niz rizika.
Studije koje su se usredotočile na CBD za trigeminalnu neuralgiju zaključile su da su ili CB1 receptor sami ili kombinacija CB1 i CB2 receptora odgovorni za antineuralgičke učinke kanabinoida. Postoji sve veći broj dokaza koji sugeriraju da bi samo aktivacija CB2 receptora mogla biti dovoljna za proizvodnju kanabinoidno posredovanih antineuralgičkih učinaka. Utvrđeno je da novi agonist CB2 receptora učinkovito smanjuje bol kod modela štakora neuropatske boli i još tri vrste boli bez značajnog utjecaja na motoričke sposobnosti. U oba pokusa, na životinjama i anegdotalno kod ljudi, mnogi ljudi smatraju da su kanabinoidi dokazali učinkovit tretman u upravljanju trigeminalnom neuralgijom.
Za svakoga tko pati od ovog užasnog poremećaja, očaj je stvaran, a većina pacijenata spremna je dati bilo što. Mnogi su ljudi uskočili na vlak CBD-a i pokušavali sami sebi pomoći, uživajući u uspjehu. Vrijeme je da svatko tko živi s TN dobije neko olakšanje iz ovog izuzetno bolnog poremećaja i ponovno počne uživati u životu.
Izvor: https://discovercbd.com/blogs/cbd-news/cbd-oil-and-trigeminal-neuralgia
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